The bioanalytical sciences provided critical data to understand the pharmacokinetics, pharmacodynamics of therapeutic molecules. This data enables the pharmaceutical scientists to design therapeutic molecules that are more effective, safe and tolerable. In the era of precision medicine other aspects of bioanalysis, such as sampling techniques, use of data from multiple platforms and technologies in a cohesive manner, imaging data come into the drug development paradigm. Are we ready to address these new aspects to a traditional science or are we behind. How do we correlate genomic data to the concentration data that we acquire? There are more questions than answers. This talk will highlight some of these concepts for us to be thinking about the future.